webber naturals 400mg Coenzyme Q10 Softgels, 60-count, 2-pack
Helps reduce the frequency of migraine headaches
Helps support cardiovascular health
Provides 400 mg of coenzyme Q10 per softgel
Added rice bran oil and natural tocopherols for improved absorption
Webber Naturals Coenzyme Q10 400 mg helps reduce the frequency of migraine headaches. Coenzyme Q10 has also been shown to reduce symptoms associated with migraine headaches such as nausea and vomiting, when taken as a prophylactic. (1-3) Coenzyme Q10 (CoQ10), also known as ubiquinone, is a naturally occurring compound in the body. Levels of this nutrient may be depleted by certain cholesterol-lowering medications. (4,5) CoQ10 can be found in animal proteins, fruits, and vegetables, but large amounts would need to be consumed to obtain enough of it. (6) Supplementation with CoQ10 supports cardiovascular health (7) and provides an antioxidant for the maintenance of good health. (8,9) Features and Benefits:Ultra-strength potencyProvides 400 mg of coenzyme Q10 per softgelDerived from a natural sourceAdded rice bran oil and natural tocopherols for improved absorption (10)No glutenSugar freeNon-GMOFree of artificial colours, preservatives, and sweetenersNo dairy, starch, wheat, yeast, soy, corn, egg, fish, shellfish, salt, or tree nutsGelatin – bovineNPN 80028384Recommended dosage (adults): 1 softgel daily preferably with a meal or as directed by a physician. Use for a minimum of 3 months to see beneficial effectsServings:120 daysCautions or warnings: Consult a physician prior to use if you are pregnant or breastfeeding, or if you are taking blood pressure medication or blood thinners. May cause nausea Consult a physician if migraine frequency increases or if associated nausea and vomiting persist or worsenKeep out of reach of childrenStorage:Protect from heat and humidityReferences:1. Hershey AD, Powers SW, Vockell AL, et al. Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine. Headache. 2007; 47(1):73-80.2. Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: a randomized controlled trial. Neurology. 2005; 64(4):713-715.3. Parohan M, Sarraf P, Javanbakht MH, et al. Effect of coenzyme Q10 supplementation on clinical features of migraine: a systematic review and dose-response meta-analysis of randomized controlled trials. Nutr Neurosci. 2019; 1-8. 4. Casagrande D, Waib PH, Jordão AA. Mechanisms of action and effects of the administration of Coenzyme Q10 on metabolic syndrome. JNIM. 2018; 13:26-32.5. Skarlovnik A, Janić M, Lunder M, et al. Coenzyme Q10 supplementation decreases statin-related mild-to-moderate muscle symptoms: a randomized clinical study. Med Sci Monit. 2014; 20:2183-2188.6. Pravst I, Zmitek K, Zmitek J. Coenzyme Q10 contents in foods and fortification strategies. Crit Rev Food Sci Nutr. 2010; 50(4):269-280.7. Rosenfeldt FL, Haas SJ, Krum H, et al. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Human Hypertens. 2007; 21(4):297-306.8. Kalpravidh RW, Wichit A, Siritanaratkul N, et al. Effect of coenzyme Q10 as an antioxidant in β-thalassemia/Hb E patients. BioFactors. 2005; 25(1-4):225-234.9. Zarei P, Rezvanfar MR, Ansarihadipour H, et al. Effects of coenzyme Q10 supplementation on the serum levels of amylase, adenosine deaminase, catalase, and total antioxidant capacity in women with type 2 diabetes mellitus: A randomized, double-blind placebo-controlled trial. J Res Med Sci. 2018; 23:91.Kaikkonen J, Nyyssönen K, Porkkala-Sarataho E, et al. Effect of oral coenzyme Q10 supplementation on the oxidation resistance of human VLD+LDL fraction: absorption and antioxidant properties of oil and granule-based preparations. Free Radic Biol Med. 1997; 22(7):1195-1202.This product is not available for delivery to the province of Quebec due to provincial restrictions.